The Agilent SureSelect v8 and Twist Exome 2.0 are the newest additions to our extensive line of exome enrichment probes, providing more options for targeting the specific gene you're looking for, including detecting rare and inherited diseases.
Discover which exome probe is best suited for my studies.
Examine some of our advanced analysis.
| Getting started on your WES project? |
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| Getting started on your WES project? |
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What are my requirements for whole exome sequencing?
| Option 1 Clinical grade |
Option 2 Cost effectiveness |
Option 3 Comprehensive |
Option 4 Mouse samples |
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|---|---|---|---|---|
| Probes | IDT: xGEN Exome Hybridization Panel | Agilent SureSelect All Exon V6 | Agilent SureSelect All Exon V8 Twist Exome 2.0 |
Agilent SureSelect XT Mouse |
| Target size | 39M | 60M | Agilent V8: 35.1M Twist 2.0: 36.5M |
49.6M |
| Database coverage |
RefSeq | CCDS, RefSeq, GENCODE | Agilent v8: CCDS, RefSeq, GENCODE Twist 2.0: CCDS, RefSeq, GENCODE, Clinvar, HCMG, Ensembl |
Ensembl, RefSeq |
| Sample types |
gDNA from blood Saliva Cell lines/ Pellets |
gDNA from blood Saliva Cell lines/ Pellets FFPE Other tissues cfDNA/ ctDNA |
gDNA from blood Saliva Cell lines/ Pellets |
gDNA from mouse |
| TAT* | within 2 weeks | within 4 weeks | 6-7 weeks | within 5 weeks |
| Price | +++ | ++ | +++ | +++ |
| Notable features |
- Sequencing performed in CAP laboratories. - The xGEN hybridization panel can capture and provide appropriate representation of samples with high GC and AT contents. - Fast turnaround time. |
- Suitable for different types of samples and vast variety of research. - Well established exome enrichment probe. |
- Comprehensive and the most up-to-date coverage of protein coding regions. Agilent V8: - Ability to cover the TERT promoter region and other hard-to-capture exons, as well as having a better uniformity of its coverage distribution. Twist 2.0: - Offers clinically relevant panels such as Clinvar, alongside other genomic databases for translational research. |
- Based on the current UCSC mm9 mouse genome and has a full coverage of the mouse exome by capturing 221,784 exons and 24,306 genes. |
*For project w/o bioinformatic analysis. TAT is from confirmation of library preparation after sample QC and is subject to change based on sample size, bioinformatic analysis and additional services.
Option 1: Clinical grade
For research projects that require clinical grade exome sequencing, our CAP certified laboratories provide services and results that are compliant to strict regulations while meeting our fast turn-around time of 10 working days. One of the probes operated by our licensed personnel includes the xGEN Exome Hybridization Panel by IDT.
Option 2: Cost effectiveness
For research projects that will require both versatility and experience with different types of samples while remaining cost-effective, we recommend the Agilent SureSelect All Exon V6 panel. The UTR spike-in for Agilent SureSelect All Exon V6 panel is also available in our offerings.
Option 3: Comprehensive
For research projects that are interested in proceeding with the most up-to-date and comprehensive coverage of protein coding regions from databases, we offer two panels for your consideration:
Agilent SureSelect All Exon V8
Notable Features: Released in 2021, Agilent SureSelect All Exon V8 is the newest probe by Agilent. The latest V8 probe not only provides more specificity and a more comprehensive coverage in comparison to the previous probe, Agilent SureSelect All Exon V7, but also made a few improvements. Some of these improvements include the ability to cover the TERT promoter region and other hard-to-capture exons, as well as having a better uniformity of its coverage distribution.
Twist Exome 2.0
Notable Features: Released in 2021, the Twist Exome 2.0, is unique in that it offers clinically relevant panels such as Clinvar, alongside other genomic databases for translational research. This will allow researchers to have more clinical insight into their research as both Clinvar and Gencode provides the ability to identify genomes linked to clinical phenotypes.
Option 4: Mouse samples
For research projects that is currently working with mouse samples for human-based research, we offer the Agilent SureSelectXT Mouse probe as an option.
Your trusted genomics partner
Getting you on an enhanced genomics research experience is the core of what we do because achieving your research goal matters. Here's why we're your trusted genomics partner:
Wide selection of probes
and services
and services
Includes the most up-to-date panels. Custom panels, DNA extractions and advanced analyses, are available.
Competitive turnaround
time (TAT)
time (TAT)
We get that your project may be time sensitive. Our sales and technical support specialists, and global lab presence will ensure that your specimens are promptly processed, with an express TAT of 10 working days.
Customized
analyses
analyses
Customized data analyses for
disease and cancer.
disease and cancer.
Clinical grade exome sequencing
Our CAP and CLIA laboratories ensures that your specimens are processed under the highest quality and in compliance to strict regulations.
Best-in-class
results
results
We enrol in certification programs as part of our commitment to provide customers with the highest quality data. Learn more about our recent Twist ProLab Certification.
One account for all
your projects
your projects
Project management on our customer service system includes online collaborative tools with working mates.
About Novogene
Novogene is a pioneer in applying cutting-edge molecular biology technology and high-performance computing to research in the fields of life science and human health. Our vision is to continue as a global leader in the delivery of genomics services and solutions. With one of the largest sequencing capacities in the world, we utilise our deep scientific knowledge, first-class customer service and unsurpassed data quality to help clients realise their research goals in the rapidly evolving world of genomics. Novogene is committed to become your trusted genomics partner.
For more information, visit novogene.com/amea-en/.
For more information, visit novogene.com/amea-en/.
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