Novogene Mass Specs Seminar

Multi-omics Strategies to Decipher Pathogenesis: Single-Cell Sequencing, DIA Proteomics and Phosphorylation Signalling

10 Sept 2026 (Thursday) | 11am - 1:30pm

Meeting Room 7C, Level 7, Duke-NUS Medical School

8 College Road, Singapore 169857

Diseases such as hypertension, chronic kidney disease, and respiratory infections involve complex molecular changes across multiple cell types and biological pathways. Understanding these changes requires technologies that can capture cellular diversity, gene regulation, and protein-level activity.

This seminar will introduce practical approaches to single-cell sequencing, including sample preparation for PBMCs and cryopreserved samples. It will also cover the combination of scRNA-seq with scATAC-seq to simultaneously profile gene expression and chromatin accessibility.

The second part will focus on DIA proteomics and phosphorylation analysis, highlighting how protein-level data can complement transcriptomic and epigenomic findings. Case studies will demonstrate how these technologies can be integrated to provide deeper insights into disease pathogenesis and host responses.

What to expect

Practical guidance on preparing PBMCs for single-cell studies, including sample processing, cell isolation, viability assessment, and quality control.
Key considerations for fresh and cryopreserved samples, with attention to handling, storage, thawing, cell recovery, and their effects on data quality.
An overview of scRNA-seq and scATAC-seq workflows, including how gene expression and chromatin accessibility can be analysed together to understand cellular diversity and gene regulation.
An introduction to DIA proteomics and phosphorylation analysis, highlighting their roles in measuring protein abundance, signalling activity, and disease-related molecular changes.
Case studies and multi-omics integration strategies in disease research, demonstrating how transcriptomic, epigenomic, proteomic, and phosphoproteomic data can reveal disease mechanisms.

Meet the Speakers

Anna FEI Jing

Principal Product Manager, NovogeneAIT Genomics

Presentation Title

From Sample to Science: Best-Practice PBMC Prep and Single-Cell Sequencing Solutions with Real-world Case Studies in Disease Research

About the Presenter

Anna is a Principal Product Manager for Single Cell Sequencing and Spatial Transcriptomics at Novogene, overseeing the service portfolio across the AMEA region — including Singapore, Japan, Korea, Australia, and Hong Kong. She brings a strong nine-year track record in next-generation sequencing. Previously, Anna served on the technical team at a local hospital, Illumina, and Thermo Fisher, where she gained unparalleled insight into the instrumentation and chemistry driving modern NGS and supported customers across academia and clinical settings. At Novogene, Anna leverages this unique cross-industry expertise to assist researchers in navigating the complexities of single-cell and spatial biology — from platform selection to addressing complex research needs.

CHAI Sin Yee

Senior Technical Solution Specialist, NovogeneAIT Genomics

Presentation Title

From Proteome Landscapes to Disease Mechanisms: DIA Proteomics, Phosphorylation Signalling, and Multi-Omics Integration

About the Presenter

Sin Yee has supported over 1000 genomics and multiomics projects, including large-scale studies involving thousands of samples. With a background in biochemistry and molecular biology, she specialises in technical consultation, NGS workflow and troubleshooting, and project management. Her expertise spans a wide range of sequencing applications, enabling her to provide solution-oriented guidance that helps researchers overcome technical challenges and achieve their research objectives.

Seminar Programme

1045

Registration

1100

Principal Product Manager Ms Anna FEI Jing From Sample to Science: Best-Practice PBMC Prep and Single-Cell Sequencing Solutions with Real-world Case Studies in Disease Research

1130

Senior Technical Solution Specialist Ms CHAI Sin Yee From Proteome Landscapes to Disease Mechanisms: DIA Proteomics, Phosphorylation Signalling, and Multi-Omics Integration

1200

Kahoot Quiz + Prize Giveaway

1230

Lunch & Networking

1330

Seminar End

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About Novogene

Novogene is a pioneer in applying cutting-edge molecular biology technology and high-performance computing to research in the fields of life science and human health. Our vision is to continue as a global leader in the delivery of genomics services and solutions. With one of the largest sequencing capacities in the world, we utilise our deep scientific knowledge, first-class customer service and unsurpassed data quality to help clients realise their research goals in the rapidly evolving world of genomics. Novogene is committed to become your trusted genomics partner.

For more information, visit amea.novogene.com